Figure 7.
Subretinal drusenoid deposit is less lipid rich than basal linear deposit. (A) The sub-RPE-BL space is normally devoid of lipid. (B) 60 µm away from panel A. BLinD (red arrowheads) is continuous with and thicker than pre-BLinD (yellow arrowheads) in the sub-RPE-BL space. BLinD is operationally distinguished from pre-BLinD by its undulating profile. SDD (orange arrowhead) is observed on top of wavy RPE, with a finely granular texture, several RPE melanosomes, and minimal osmophilia relative to BLinD. A choroidal lipid globule (g) is deep gray and serves as a positive control for osmophilic lipids.53 Eighty-seven-year-old man. Green arrowheads, external limiting membrane. Scale bar in B applies to A and B.