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. 2021 Jan 29;41(1):BSR20202269. doi: 10.1042/BSR20202269

Table 7. Prediction of molecular interaction of Cyclin D1 with other proteins using STRING.

Predicted functional partners Confidence scores* Prediction for specific action
CDK4
Cyclin-dependent kinase 4
0.995 Binding, activation, catalysis, reaction, inhibition, expression with inhibition, and post-translational modification
CDK6
Cyclin-dependent kinase 6
0.880 Binding, post-translational modification, catalysis, reaction, and inhibition
CDKN1A
Cyclin-dependent kinase inhibitor 1
0.993 Binding, activation, catalysis, reaction, and inhibition
IFNAR1
Interferon alpha/beta receptor 1
0.993 No direct predicted action
MCM10
Protein MCM10 homolog
0.872 No direct predicted action
CDK2
Cyclin-dependent kinase 2
0.853 Binding, activation, catalysis, reaction, and inhibition
CDKN1B
Cyclin-dependent kinase inhibitor 1B
0.689 Binding, inhibition catalysis, and reaction
CDKN1C
Cyclin-dependent kinase inhibitor 1C
0.814 Binding, reaction, and inhibition
CDK1
Cyclin-dependent kinase 1
0.781 Binding, activation, catalysis, reaction, and inhibition
ORC4
Origin recognition complex subunit 4
0.722 No direct predicted action
*

Confidence score = how likely STRING judges an interaction to be true. 0–1, where 1 is highest confidence and ≤ 0.5 represents a false positive interaction.