Table 2.

Relationship between PDQ-39 scores and presence/absence of “OFF” episodes (N = 722)

PDQ-39 dimensions	Coefficient (95% CI)a	P value
Mobility	+ 7.9 (4.4, 11.4)	<  0.001
Activities of daily living	+ 6.7 (3.2, 10.1)	<  0.001
Emotional well-being	+ 4.5 (0.7, 8.3)	0.019
Stigma	+ 3.0 (−0.1, 6.1)	0.057
Social support	+ 2.3 (−0.7, 5.3)	0.134
Cognitions	+ 6.5 (3.5, 9.4)	<  0.001
Communication	+ 9.0 (6.0, 11.9)	<  0.001
Bodily discomfort	+ 1.7 (−3.0, 6.5)	0.470
Summary index	+ 5.2 (2.8, 7.6)	<  0.001

^aEffect coefficient for difference between patients with/without “OFF” episodes from linear regression; + indicates a higher score on the PDQ-39 dimension or summary index, indicating poorer health-related quality of life, in patients with “OFF” episodes compared with patients without “OFF” episodes

CI confidence interval; PDQ-39 39-item Parkinson’s Disease Questionnaire