Table 4.

Relationship between EQ-5D scores and presence/absence of “OFF” episodes (N = 722)

EQ-5D dimensions	Odds ratio (95% CI)a	P value
Mobility	2.1 (1.3, 3.5)	0.002
Self-care	1.4 (0.9, 2.1)	0.112
Usual activities	2.6 (1.8, 3.7)	<  0.001
Pain/discomfort	1.2 (0.8, 1.8)	0.467
Anxiety/depression	1.6 (1.1, 2.2)	<  0.001
	Coefficient (95% CI)b	P value
Health utility index	−0.04 (−0.07, −0.02)	<  0.001
VAS	−6.75 (−9.49, −4.00)	<  0.001

^aOdds ratio for difference between patients with/without “OFF” episodes from ordered logistic regression on the categorical EQ-5D responses (indicating no problem/some problem/extreme problem). ^bEffect coefficient for difference between patients with/without “OFF” episodes from linear regression on EQ-5D utility index and VAS; − indicates a lower score on the EQ-5D utility index or VAS, indicating poorer health status, in patients with “OFF” episodes compared with patients without “OFF” episodes

CI confidence interval; EQ-5D EuroQol 5-Dimension; VAS visual analog scale