Table 1.
Variable | Total (n = 860) | Men (n = 462) | Women (n = 398) | RR (male: female) (95% CI) | P value |
---|---|---|---|---|---|
Oral ulcer | 856 (99.5) | 459 (99.4) | 397 (99.7) | 1.00 (0.99, 1.00) | P = 0.628 |
Genital ulcer | 663 (77.1) | 328 (71.0) | 335 (84.2) | 0.84 (0.79, 0.91) | P < 0.0001 |
Skin lesions | 477 (55.5) | 273 (59.1) | 204 (51.3) | 1.15 (1.02, 1.30) | P = 0.021 |
Erythema nodosum | 344 (40.0) | 183 (39.6) | 161 (40.5) | 0.98 (0.83, 1.15) | P = 0.802 |
Folliculitis | 208 (24.2) | 138 (29.9) | 70 (17.6) | 1.70 (1.32, 2.19) | P < 0.0001 |
Arthritis | 104 (12.1) | 59 (12.8) | 45 (11.3) | 1.13 (0.79, 1.63) | P = 0.511 |
Arthralgia | 77 (9.0) | 46 (10.0) | 31 (7.8) | 1.28 (0.83, 1.98) | P = 0.267 |
Ocular involvement | 155 (18.0) | 113 (24.5) | 42 (10.6) | 2.32 (1.67, 3.22) | P < 0.0001 |
Anterior uveitis | 18 (2.1) | 9 (1.9) | 9 (2.3) | 0.86 (0.35, 2.15) | P = 0.749 |
Panuveitis | 137 (15.9) | 104 (22.5) | 33 (8.3) | 2.72 (1.88, 3.92) | P < 0.0001 |
Intestinal involvement | 178 (20.7) | 92 (19.9) | 86 (21.6) | 0.92 (0.71, 1.20) | P = 0.541 |
Intestinal erosion | 7 (0.8) | 3 (0.6) | 4 (1.0) | 0.65 (0.15, 2.87) | P = 0.710 |
Intestinal ulcer | 141 (16.4) | 71 (15.4) | 70 (17.6) | 0.87 (0.65, 1.18) | P = 0.381 |
Intestinal perforation | 30 (3.5) | 18 (3.9) | 12 (3.0) | 1.29 (0.63, 2.65) | P = 0.483 |
Esophageal ulcer | 36 (4.2) | 21 (4.5) | 15 (3.8) | 1.21 (0.63, 2.31) | P = 0.571 |
Vascular involvement | 73 (8.5) | 51 (11.0) | 22 (5.5) | 2.00 (1.23, 3.23) | P = 0.004 |
Deep venous thrombosis | 29 (3.4) | 22 (4.8) | 7 (1.8) | 2.71 (1.17, 6.27) | P = 0.015 |
Major vein (vena cava, hepatic) thrombosis | 7 (0.8) | 6 (1.3) | 1 (0.3) | 5.17 (0.63, 42.75) | P = 0.131 |
Arterial thrombosis or aneurysms | 46 (5.3) | 32 (6.9) | 14 (3.5) | 1.97 (1.07, 3.64) | P = 0.027 |
Cardiac lesion | 44 (5.1) | 38 (8.2) | 6 (1.5) | 5.46 (2.33, 12.77) | P < 0.0001 |
CNS disorder | 31 (3.6) | 24 (5.2) | 7 (1.8) | 2.95 (1.29, 6.78) | P = 0.007 |
Parenchymal involvements | 23 (2.7) | 16 (3.5) | 7 (1.8) | 1.97 (0.82, 4.74) | P = 0.122 |
MDS | 6 (0.7) | 1 (0.2) | 5 (1.3) | 0.17 (0.02, 1.47) | P = 0.101 |
Values presented as n (%) unless otherwise stated. CNS central nervous system, MDS myelodysplastic syndrome