Table 2.
Mortality rates in male and female study participants with valid information on vital status on October 31 2015, stratified by quartiles of triglycerides, HDL cholesterol, and TG:HDL
| N | Events | Percent events | Events per 1000 patient-years (95% CI), unadjusted | p | Events per 1000 patient-years (95% CI), age- & gender-adjusted | p | |
|---|---|---|---|---|---|---|---|
| Triglycerides | |||||||
| Males | 0.507 | < 0.0001 | |||||
| I | 2219 | 539 | 24.3 | 33.09 (30.41–36.00) | Ref | 22.71 (20.70–24.91) | Ref |
| II | 2224 | 538 | 24.2 | 32.75 (30.09–35.64) | 0.865 | 23.36 (21.31–25.61) | 0.640 |
| III | 212 | 569 | 25.7 | 35.34 (32.56–38.37) | 0.273 | 26.25 (24.01–28.69) | 0.016 |
| IV | 2247 | 541 | 24.1 | 32.57 (29.94–35.44) | 0.796 | 30.15 (27.63–32.90) | < 0.0001 |
| Females | 0.471 | 0.154 | |||||
| I | 1651 | 330 | 20.0 | 26.46 (23.75–29.47) | Ref | 18.72 (16.65–21.05) | Ref |
| II | 1710 | 374 | 21.9 | 29.36 (26.53–32.49) | 0.167 | 20.68 (18.49–23.12) | 0.188 |
| III | 1701 | 347 | 20.4 | 27.11 (24.40–30.11) | 0.753 | 20.27 (18.11–22.70) | 0.300 |
| IV | 1692 | 364 | 21.5 | 28.75 (25.94–31.86) | 0.274 | 22.25 (19.93–24.84) | 0.023 |
| HDL cholesterol | |||||||
| Males | 0.023 | < 0.0001 | |||||
| I | 2038 | 542 | 26.6 | 36.98 (33.99–40.22) | 0.210 | 32.14 (29.42–35.11) | < 0.0001 |
| II | 2200 | 509 | 23.1 | 31.21 (28.61–34.04) | 0.120 | 25.08 (22.88–27.49) | 0.304 |
| III | 2377 | 559 | 23.5 | 31.70 (29.17–34.44) | 0.184 | 22.76 (20.79–24.91) | 0.564 |
| IV | 2287 | 577 | 25.2 | 34.30 (31.61–37.21) | Ref | 23.55 (21.53–25.76) | Ref |
| Females | < 0.0001 | < 0.0001 | |||||
| I | 1654 | 443 | 26.8 | 37.29 (33.98–40.93) | < 0.0001 | 28.93 (26.12–32.05) | < 0.0001 |
| II | 1709 | 322 | 18.8 | 24.79 (22.22–27.65) | 0.985 | 18.77 (16.70–21.09) | 0.136 |
| III | 176 | 305 | 19.4 | 25.62 (22.90–28.67) | 0.685 | 18.83 (16.72–21.22) | 0.131 |
| IV | 1815 | 345 | 19.0 | 24.82 (22.33–27.58) | Ref | 16.71 (14.88–18.76) | Ref |
| TG:HDL | |||||||
| Males | 0.656 | < 0.0001 | |||||
| I | 2223 | 535 | 24.1 | 32.63 (29.97–35.51) | Ref | 21.62 (19.69–23.74) | Ref |
| II | 2228 | 537 | 24.1 | 32.64 (30.00–35.53) | 0.992 | 23.38 (21.33–25.62) | 0.202 |
| III | 2226 | 565 | 25.4 | 34.87 (32.11–37.87) | 0.270 | 26.80 (24.53–29.29) | < 0.0001 |
| IV | 2225 | 550 | 24.7 | 33.58 (30.89–36.51) | 0.633 | 30.80 (28.23–33.59) | < 0.0001 |
| Females | 0.051 | < 0.0001 | |||||
| I | 1686 | 325 | 19.3 | 25.31 (22.70–28.22) | Ref | 17.33 (15.39–19.52) | Ref |
| II | 1689 | 347 | 20.5 | 27.33 (24.60–30.36) | 0.321 | 19.66 (17.54–22.03) | 0.103 |
| III | 1690 | 354 | 21.0 | 27.98 (25.22–31.06) | 0.191 | 20.69 (18.49–23.16) | 0.022 |
| IV | 689 | 389 | 23.0 | 31.15 (28.21–344.1) | 0.006 | 24.41 (21.93–27.17) | < 0.0001 |
TG:HDL triglyceride:HDL cholesterol ratio, CI confidence interval