Figure 4.
Post-nitro-l-arginine methyl ester (l-NAME) plateau % of maximum cutaneous vascular conductance (%CVCmax) responses. Group responses are shown as means ± SD and were compared with a 3-way ANOVA. At control sites, the post-l-NAME plateau was greater in prehypertensive non-Hispanic Whites (PreHT NHW, n = 10 participants) and prehypertensive non-Hispanic Blacks (PreHT NHB, n = 10 participants) relative to normotensive non-Hispanic Whites (NT NHW, n = 10 participants). The PreHT NHW post-l-NAME plateau at control sites was significantly greater than that for normotensive non-Hispanic Blacks (NT NHB, n = 10 participants). There was no difference between NT NHW and NT NHB at control sites. At 1400W sites, the post-l-NAME plateau was significantly reduced compared to the respective control sites for PreHT NHW and NT NHB, but there was no observed effect of 1400W for NT NHW or PreHT NHB. The 1400W post-l-NAME plateau was significantly greater in PreHT NHB relative to both NT NHW and NT NHB. *P < 0.05 vs. NT NHW within a treatment site; #P < 0.05 vs. NT NHB within a treatment site; $P < 0.05 vs. respective control site.