Table 2.

Hemodynamics reveals no difference between 6- and 10-wk HF

	n	Heart Rate, beats/min	EDP, mmHg	SP, mmHg	(+)dP/dt, mmHg/s	(−)dP/dt, mmHg/s	Tau, ms	PDP, mmHg
SHAM	10	286 ± 7	6 ± 1	140 ± 4	7,612 ± 299	−7,554 ± 242	18.6 ± 0.5	180 ± 5
HF-6 wk	20	248 ± 5*	25 ± 2*	110 ± 4*	4,477 ± 251*	−3,031 ± 202*	31.7 ± 2.3*	121 ± 8*
HF-10 wk	12	246 ± 5*	22 ± 2*	122 ± 6*	5,084 ± 308*	−3204 ± 381*	34.1 ± 2.2*	129 ± 7*

Summary of the invasive hemodynamic results (means ±SE; n = number of rats in sample size) from SHAM rats, 6-wk heart failure (HF) rats, and 10-wk HF rats. Hemodynamic data were collected at the terminal procedure, immediately before electrophysiologic assessment. EDP, left ventricular end-diastolic pressure; SP, left ventricular systolic pressure; (+)/(−)dP/dt, positive/negative change in ventricular pressure with respect to time; Tau, left ventricular relaxation time constant; PDP, left ventricular peak developed pressure. While overt differences are seen between SHAM and 6-wk HF (*P < 0.05, ANOVA-Tukey’s honestly significant difference or Kruskal-Wallis ANOVA on ranks and Dunn’s Method), as well as between SHAM and 10-wk HF (*P < 0.05), no differences are observed between 6-wk HF and 10-wk HF.