Figure 1.

C-reactive protein (CRP) and soluble ICAM-1 (sICAM-1) in serum (colored online). A and B: profiles of CRP and soluble ICAM-1 (sICAM-1) extracted from serum of all subjects before (pre, blue arrow) and after (post, red arrow) e-cigarette (e-cig) vaping. Solid black arrow denotes the point in time of e-cig aerosol inhalation. CRP and ICAM-1 were assayed using quantitative ELISA and quantified using reference curves of standards provided by the manufacturer (see materials and methods). C and D: box and whiskers plots of CRP and sICAM-1 pre- and postvaping, plotted in log scale. Group average and median are indicated by white circle and horizontal bar, respectively; ***P < 0.0005.