Table 1.
Comparison of demographic and basal clinical characteristics of patients between Xuebijing group and control group.
| Clinical characteristics | Xuebijing group (n = 29) | Control group (n = 28) | P value |
|---|---|---|---|
| Age, yr, mean (SD) | 60.26(15.62) | 56.35(18.28) | 0.286 |
| 18–50, n (%) | 12 (41.3) | 13 (46.4) | 0.872 |
| 50-80, n(%) | 17(58.6) | 15 (53.6) | 0.864 |
| Systolic blood pressure, mmHg, mean (SD) | 126.63 (22.36) | 126.52 (23.16) | 0.852 |
| Respiratory rate, breaths/min, mean (SD) | 29.25(6.42) | 29.91 (6.28) | 0.914 |
| Heart rate, beats/min, mean(SD) | 108.26 (19.65) | 110.32 (19.57) | 0.863 |
| Temperature,°C, mean (SD) | 38.26 (1.06) | 38.36 (1.04) | 0.936 |
| Pao2/Fio2, mean (SD) | 176.25 (55.06) | 178.34 (54.93) | 0.762 |
| Comorbidities, n (%) | |||
| Hypertension,n (%) | 12 (41.3) | 18(64.3) | 0.562 |
| Diabetes mellitus, n (%) | 3 (10.34) | 5(17.85) | 0.476 |
| Heart disease,n(%) | 2(6.9) | 1(3.57) | 0.554 |
| Cerebral infarction,n(%) | 3(10.34) | 2(7.14) | 0.640 |
| Leucocytes, 109 cells/L, mean (SD) | 7.37(4.42) | 5.80(2.56) | 0.126 |
| Lymphocyte, 109 cells/L, mean (SD) | 0.954(0.38) | 1.06(0.42) | 0.349 |
| C-reactive protein, mg/L, mean (SD) | 37.65(46.6) | 23.47(20.37) | 0.159 |
| IL-6,ng/ml,mean(SD) | 0.060(0.011) | 0.058(0.010) | 0.891 |
| IL-8,ng/ml,mean(SD) | 0.36(0.17) | 0.34(0.16) | 0.934 |
| TNF-α,pg/ml,mean(SD) | 38.42(10.12) | 37.85(10.46) | 0.736 |
| Total PSI score, mean (SD) | 118.47(35.32) | 120.36(32.16) | 0.692 |
| Systemic Inflammatory Response Syndrome score, mean (SD) | 3.12(0.66) | 3.08(0.71) | 0.964 |
| Antimicrobial treatment,n(%) | |||
| β-lactams enzyme inhibitors,n(%) | 8 (27.58) | 9 (32.14) | 0.947 |
| Quinolinones,n(%) | 4 (13.79) | 3 (10.71) | 0.731 |
| Fluconazole,n(%) | 2 (6.9) | 1 (3.57) | 0.554 |
| Carbapenem,n(%) | 3 (10.34) | 2 (7.14) | 0.640 |
| Mechanical ventilation, n (%) | |||
| IMV, n (%) | 0 | 0 | |
| NMV, n (%) | 4(13.79) | 5(17.85) | 0.583 |
| Intranasal oxygen (low flow), n (%) | 26(89.65) | 25(89.28) | 0.985 |
Abbreviations: IL-6, Interleukin-6; IL-8,Interleukin-8;TNF-α,tumor necrosis factor-α; PSI, Pneumonia severity index;IMV, invasive mechanical ventilation; NMV, noninvasive mechanical ventilation (including high flow supply and face mask).