Table 4.
Complications of allogeneic hematopoietic cell transplant during 2013-2017 |
Number of patients* |
Hazard Ratio for Day-200 Non- Relapse Mortality (95% CI) |
---|---|---|
Peak total serum bilirubin ≥68.4 μmol/L (4 mg/dL) | 123 | 11.94 (8.16 – 17.47) |
Peak total serum bilirubin ≥171 μmol/L (10 mg/dL) | 29 | 33.85 (20.06 – 57.11) |
Serum creatinine 2-times baseline | 254 | 6.63 (4.60 – 9.57) |
Serum creatinine 3-times baseline | 67 | 15.47 (9.97 – 24.01) |
Renal Replacement Therapy | 39 | 20.80 (13.03 – 33.22) |
Mechanical ventilation | 77 | 15.85 (10.72 – 23.44) |
Jaundice + Renal Replacement Therapy + Mechanical ventilation | 19 | 36.70 (19.31 – 69.77) |
Any CMV infection† | 501 | 1.23 (0.73 – 2.08) |
CMV DNA >250 IU/mL† | 288 | 2.33 (1.42 – 3.84) |
CMV DNA >1000 IU/mL† | 138 | 2.82 (1.68 – 4.75) |
CMV disease b | 24 | 2.00 (0.72 – 5.56) |
Gram negative bacteremia | 74 | 5.16 (3.22 – 8.24) |
Invasive mold infection | 42 | 9.73 (5.83 – 16.22) |
GVHD grade 2-4 | 784 | 1.45 (0.95 – 2.22) |
GVHD grade 3-4 | 135 | 5.29 (3.59 – 7.81) |
See Table 3, Frequency of events among all patients transplanted during 2013-2017.
Among CMV-seropositive patients only.