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. 2021 Jan 21;14(1):dmm046995. doi: 10.1242/dmm.046995

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© 2021. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 1. — Immune profiling of non-UC donors and UC patients. (A) Representative flow cytometric images of CD4⁺ CD134⁺ and CD14⁺ CD252⁺ (OX40L) cells in PBMCs from non-UC and UC donors. (B) Frequencies of activated CD4⁺ T cells (CD134⁺ and CD69⁺) and CD252-expressing CD14⁺ monocytes depicted as boxplots. Boxes represent upper and lower quartiles; whiskers represent variability, and outliers are plotted as individual points. For comparison of groups, Student's unpaired t-test was conducted. Donor A-C refers to donors of PBMCs used in the animal study. ***P<0.001, *P<0.05, ^#P<0.1. (C) Correlation analysis of OX40L (CD252) with TH1 and TH2 CD4⁺ T cells. The numbers display Pearson's product-moment correlation values (cor), P-values (P) and the 95% confidence interval (CI).