a, Representative traces of the spontaneous firing rate of CRH neurons 2 hrs following kainic acid-induced seizures in Gabrd/Crh mice and Cre−/− littermates, and in vehicle treated controls. b, The average firing rate of CRH neurons 2 hrs following kainic acid-induced seizures in Gabrd/Crh mice and Cre−/− littermates, and in vehicle treated controls. n = 15 – 16 slices, 4 – 5 mice per experimental group; * denotes p<0.05 using a two-way ANOVA