Table 1.
Pretreatment and treatment characteristics for all and PSM patients per SIRI status.
| Covariate | All patients (N = 876) | SIRI ≥ 1.9 (N = 487) | SIRI < 1.9 (N = 389) | P value | PSM patients (N = 608) | SIRI ≥ 1.9 (N = 304) | SIRI < 1.9 (N = 304) | P value |
|---|---|---|---|---|---|---|---|---|
| Median age, y (range) | 64 (29–79) | 65 (31–79) | 63 (29–79) | 0.56 | 65 (31–79) | 64 (31–79) | 65 (34–79 | 0.87 |
|
| ||||||||
| Age group, y (%) | ||||||||
| ≤70 years | 772 (88.1) | 428 (86.7) | 344 (88.4) | 0.64 | 542 (89.1) | 270 (88.8) | 272 (89.5) | 0.82 |
| >70 years | 104 (11.9) | 59(13.3) | 45 (11.6) | 66 (10.9) | 34 (11.2) | 32 (10.5) | ||
|
| ||||||||
| Gender, n (%) | ||||||||
| Male | 539 (61.5) | 291 (59.8) | 248 (63.8) | 0.32 | 368 (60.5) | 180 (59.2) | 188 (61.8) | 0.49 |
| Female | 337 (38.5) | 196 (40.2) | 141 (36.2) | 240 (39.5) | 124 (40.8) | 116 (38.2) | ||
|
| ||||||||
| KPS, n (%) | ||||||||
| 90–100 | 751 (71.7) | 269 (71.0) | 482 (72.0) | 0.64 | 442 (72.7) | 219 (72.0) | 223 (73.4) | 0.79 |
| 70–80 | 297 (28.3) | 110 (29.0) | 187 (28.0) | 166 (27.3) | 85 (28.0) | 81 (26.6) | ||
|
| ||||||||
| Histology, n (%) | ||||||||
| AC | 567 (54.1) | 212 (55.9) | 355 (53.1) | 0.39 | 326 (53.6) | 157 (51.6) | 169 (55.6) | 0.32 |
| SCC | 481 (45.9) | 167 (44.1) | 314 (46.9) | 282 (46.4) | 147 (48.4) | 135 (44.4) | ||
|
| ||||||||
| T-stage, n (%) | ||||||||
| 1–2 | 361 (34.4) | 116 (30.6) | 245 (36.6) | 0.28 | 254 (41.8) | 130 (42.8) | 124 (40.8) | 0.55 |
| 3–4 | 687 (65.6) | 263 (69.4) | 424 (63.4) | 354 58.2) | 174 (57.2) | 180 (59.2) | ||
|
| ||||||||
| N-stage, n (%) | ||||||||
| 2 | 531 (50.7) | 195 (51.5) | 336 (50.2) | 0.55 | 317 (52.1) | 161 (53.0) | 156 (51.3) | 0.76 |
| 3 | 517 (49.3) | 184 (48.5) | 333 (49.8) | 291 (47.9) | 143 (47.0) | 148 (48.7) | ||
|
| ||||||||
| Tumor stage, n (%) | ||||||||
| IIIB | 617 (58.9) | 217 (57.3) | 400 (59.8) | 0.67 | 369 (60.7) | 188 (61.8) | 181 (59.5) | 064 |
| IIIC | 431 (41.1) | 162 (42.7) | 269 (40.2) | 239 (39.3) | 116 (38.2) | 123 (40.5) | ||
Abbreviations. SIRI: systemic inflammation response index; PSM: propensity score matching; KPS: Karnofsky performance score; AC: adenocarcinoma; SCC: squamous cell carcinoma; T: tumor; N: node.