Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 30;36(1):37–55. doi: 10.1007/s10654-020-00688-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — Spline regression curves for the association between early adulthood body mass index and breast cancer risk, the Pooling Project of Prospective Studies of Diet and Cancer, with reference 19 kg/m². Panel A shows the associations for overall premenopausal breast cancer (pre; p value, test for nonlinearity = 0.088), overall postmenopausal breast cancer among never users of hormone therapy (post never; p value, test for nonlinearity = 0.509), and overall postmenopausal breast cancer among ever users of hormone therapy (post ever; p value, test for nonlinearity = 0.068). Panel B shows the associations for premenopausal breast cancer subtypes defined by estrogen receptor (ER) and progesterone receptor (PR) status. The p value, test for nonlinearity = 0.090 for ER+, 0.469 for ER−, 0.047 for PR+, 0.271 for PR−, 0.074 for ER+ PR+, 0.178 for ER+ PR−, and 0.347 for ER−PR− breast cancer. Panel C shows the associations for postmenopausal breast cancer subtypes defined by ER and PR status among never users of hormone therapy. The p value, test for nonlinearity = 0.544 for ER+, 0.130 for ER−, 0.305 for PR+, 0.074 for PR−, 0.390 for ER+ PR+, 0.060 for ER+ PR−, and 0.116 for ER−PR− breast cancer. Models were adjusted for the same factors as in Fig. 2