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. 2021 Jan 15;13(1):210–222.

Figure 6.

Figure 6

Schisandrin C downregulated the Swiprosin-1/IFN-γ-Rβ signaling pathway, in high-glucose-stimulated RAW264.7 cells. RAW264.7 cells were differentiated and pretreated with D-glucose (30 mM), for 12 h, and then treated with Schisandrin C (20-80 µM), for 48 h. A. Swiprosin-1 and IFN-γ-Rβ expression levels were analyzed by western blot analysis, using β-actin as a loading control. B. p-JAK2, p-STAT1, and p-STAT3 expression levels were analyzed by western blot analysis, using β-actin as a loading control. Representative blots are shown, with densitometry analysis. Original, full-size blots are presented in Figure S2. Data are expressed as the mean ± S.D. ##P < 0.01 vs. control; **P < 0.01, *P < 0.05 vs. model.