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. 2021 Jan 15;13(1):360–371.

Table 3.

Multivariate analysis for OS and CSS after PSM

Characteristics OS CSS


HR (95% CI) P value HR (95% CI) P value
Age (Years)
    30-49 Reference Reference
    50-69 0.746 (0.300, 1.854) 0.528 1.157 (0.377, 3.551) 0.799
    70-84 0.840 (0.323, 2.187) 0.721 1.201 (0.375, 3.851) 0.758
Gender
    Male Reference Reference
    Female 0.558 (0.339, 0.919) 0.022 0.597 (0.327, 1.088) 0.092
Race
    White Reference Reference
    Black 1.708 (0.999, 2.923) 0.051 1.379 (0.667, 2.849) 0.386
    Other 0.570 (0.324, 1.005) 0.052 0.510 (0.279, 0.933) 0.029
Year of diagnosis
    2004-2007 Reference Reference
    2008-2011 0.744 (0.442, 1.255) 0.268 0.585 (0.310, 1.102) 0.097
    2012-2015 0.763 (0.462, 1.259) 0.290 0.510 (0.281, 1.069) 0.029
Marital status
    Married Reference Reference
    Single 0.818 (0.544, 1.229) 0.333 0.853 (0.517, 1.408) 0.535
    Other 1.214 (0.545, 2.704) 0.635 1.624 (0.695, 3.796) 0.263
AJCC staging
    I Reference Reference
    II 1.250 (0.768, 2.035) 0.370 1.366 (0.762, 2.447) 0.295
    III 2.335 (1.402, 3.889) 0.001 2.129 (1.158, 3.913) 0.015
    IV 5.475 (2.726, 10.994) <0.001 5.582 (2.535, 12.291) <0.001
    Unknown 0.666 (0.268, 1.658) 0.382 0.789 (0.225, 2.767) 0.711
Tumor number
    1 Reference Reference
    2 1.282 (0.802, 2.050) 0.299 1.185 (0.427, 3.291) 0.745
    3 0.389 (0.091, 1.658) 0.202 N
Chemotherapy
    Yes Reference Reference
    No/Unknown 1.001 (0.631, 1.586) 0.998 0.864 (0.496, 1.507) 0.607
Surgery
    Transplantation Reference Reference
    Liver resection 2.189 (1.056, 4.538) 0.035 4.100 (1.567, 10.725) 0.004
    Non-liver resection 3.346 (1.635, 8.847) 0.001 6.336 (2.440, 16.452) <0.001
Radiotherapy
    Internal radiotherapy Reference Reference
    External radiotherapy 1.706 (1.134, 2.566) 0.010 1.828 (1.117, 2.990) 0.016
    Internal and external radiotherapy 0.925 (0.109, 7.824) 0.943 1.388 (0.128, 15.037) 0.787
    Unknown 0.689 (0.202, 2.354) 0.552 0.840 (0.233, 3.022) 0.789
Time of radiotherapy
    Pre-surgery Reference Reference
    Post-surgery 1.702 (1.154, 2.510) 0.007 2.131 (1.296, 3.504) 0.003