Table 3.
Characteristics | OS | CSS | ||
---|---|---|---|---|
|
|
|||
HR (95% CI) | P value | HR (95% CI) | P value | |
Age (Years) | ||||
30-49 | Reference | Reference | ||
50-69 | 0.746 (0.300, 1.854) | 0.528 | 1.157 (0.377, 3.551) | 0.799 |
70-84 | 0.840 (0.323, 2.187) | 0.721 | 1.201 (0.375, 3.851) | 0.758 |
Gender | ||||
Male | Reference | Reference | ||
Female | 0.558 (0.339, 0.919) | 0.022 | 0.597 (0.327, 1.088) | 0.092 |
Race | ||||
White | Reference | Reference | ||
Black | 1.708 (0.999, 2.923) | 0.051 | 1.379 (0.667, 2.849) | 0.386 |
Other | 0.570 (0.324, 1.005) | 0.052 | 0.510 (0.279, 0.933) | 0.029 |
Year of diagnosis | ||||
2004-2007 | Reference | Reference | ||
2008-2011 | 0.744 (0.442, 1.255) | 0.268 | 0.585 (0.310, 1.102) | 0.097 |
2012-2015 | 0.763 (0.462, 1.259) | 0.290 | 0.510 (0.281, 1.069) | 0.029 |
Marital status | ||||
Married | Reference | Reference | ||
Single | 0.818 (0.544, 1.229) | 0.333 | 0.853 (0.517, 1.408) | 0.535 |
Other | 1.214 (0.545, 2.704) | 0.635 | 1.624 (0.695, 3.796) | 0.263 |
AJCC staging | ||||
I | Reference | Reference | ||
II | 1.250 (0.768, 2.035) | 0.370 | 1.366 (0.762, 2.447) | 0.295 |
III | 2.335 (1.402, 3.889) | 0.001 | 2.129 (1.158, 3.913) | 0.015 |
IV | 5.475 (2.726, 10.994) | <0.001 | 5.582 (2.535, 12.291) | <0.001 |
Unknown | 0.666 (0.268, 1.658) | 0.382 | 0.789 (0.225, 2.767) | 0.711 |
Tumor number | ||||
1 | Reference | Reference | ||
2 | 1.282 (0.802, 2.050) | 0.299 | 1.185 (0.427, 3.291) | 0.745 |
3 | 0.389 (0.091, 1.658) | 0.202 | N | |
Chemotherapy | ||||
Yes | Reference | Reference | ||
No/Unknown | 1.001 (0.631, 1.586) | 0.998 | 0.864 (0.496, 1.507) | 0.607 |
Surgery | ||||
Transplantation | Reference | Reference | ||
Liver resection | 2.189 (1.056, 4.538) | 0.035 | 4.100 (1.567, 10.725) | 0.004 |
Non-liver resection | 3.346 (1.635, 8.847) | 0.001 | 6.336 (2.440, 16.452) | <0.001 |
Radiotherapy | ||||
Internal radiotherapy | Reference | Reference | ||
External radiotherapy | 1.706 (1.134, 2.566) | 0.010 | 1.828 (1.117, 2.990) | 0.016 |
Internal and external radiotherapy | 0.925 (0.109, 7.824) | 0.943 | 1.388 (0.128, 15.037) | 0.787 |
Unknown | 0.689 (0.202, 2.354) | 0.552 | 0.840 (0.233, 3.022) | 0.789 |
Time of radiotherapy | ||||
Pre-surgery | Reference | Reference | ||
Post-surgery | 1.702 (1.154, 2.510) | 0.007 | 2.131 (1.296, 3.504) | 0.003 |