Skip to main content
. 2021 Jan 1;11(7):3167–3182. doi: 10.7150/thno.52028

Figure 5.

Figure 5

Influence of Apo-Lf and Holo-Lf on the expression of SLC7a11, GPX-4, and apoptosis: (A-D) Western blot analysis of SLC7a11, GPX-4, Bax, and Bcl-2 in MDA-MB-231 (A/C) and MCF-7 cells (B/D) incubated with DMSO, erastin (2 μM), Apo-Lf (400 μg/mL) and Holo-Lf (400 μg/mL). The total grey intensity of each protein was normalized to the grey intensity of an appropriate protein in cells treated with DMSO. (E/F) Percentage of total apoptosis in MDA-MB-231 and MCF-7 cells (n = 3). Data are shown as mean ± SD. *Compared with DMSO group P < 0.05. **Compared with DMSO group P < 0.01. #Compared with erastin group P < 0.05. ##Compared with erastin group P < 0.01.