Table 3.
Predictors of jaundice clearance at the 6th postoperative month.
| Character | Jaundice clearance No = 138 |
No clearance No = 272 |
P-value Univariate analysis |
P-value Multivariate analysis |
|---|---|---|---|---|
| Age(days) (Mean ± SD) | 63.1 ± 14.2 | 73.5 ± 18.1 | 0.000 | >0.05 |
| Age category A (<60 days) B (60–90 days) C (>90 days) |
47 (34.1%) 84 (60.9%) 7 (5.1%) |
43 (15.8%) 141 (51.8%) 88 (32.4%) |
0.000 | >0.05 |
| Gender Males Females |
63 (45.7%) 75 (54.3%) |
123 (45.2%) 149 (54.8%) |
<0.05 | |
| Type of BA III III, cystic |
123 (89.1%) 15 (10.9%) |
267 (98.2%) 5 (1.8%) |
0.000 | 0.1 |
| Associated anomalies | 2 (1.4%) | 27 (9.9%) | 0.001 | >0.05 |
| BASM | 1 (0.7%) | 12 (4.4%) | 0.034 | >0.05 |
| Preoperative labs (Mean ± SD) TB(mg/dL) DB(mg/dL) AST(U/L) ALT(U/L) Alka phos(U/L) GGT(U/L) Alb(g/dL) INR Platelets (K/uL) |
10.8 ± 3.5 7.8 ± 2.6 160.6 ± 68.3 137.8 ± 74.6 588.9 ± 288.7 1078.8 ± 799.1 3.8 ± 0.5 1 ± 0.06 436.7 ± 162.5 |
12.9 ± 3.6 9.9 ± 3.3 236.2 ± 142.4 163.2 ± 305.1 635.9 ± 273.2 960.7 ± 731.8 3.4 ± 0.6 1.05 ± 0.1 398.3 ± 199.5 |
0.000 0.000 0.000 <0.05 0.1 <0.05 0.000 0.000 0.05 |
>0.05 0.003 0.001 >0.05 >0.05 >0.05 >0.05 |
| Portal tracts ductal and/or ductular proliferation Mild Moderate Marked |
119 (86.2%) 17 (12.3%) 2 (1.4%) |
93 (34.2%) 119 (43.8%) 60 (22.1%) |
0.000 | 0.03 |
| Portal tract fibrosis F0 F1 F2 F3 F4 |
11 (8%) 103 (74.6%) 19 (13.8%) 5 (3.6%) 0 |
6 (2.2%) 87 (32%) 125 (46%) 35 (12.9%) 19 (7%) |
0.000 | >0.05 |
| Presence of portal tracts macrophages | 44 (31.9%) | 186 (68.4%) | 0.000 | >0.05 |
| Presence of portal tracts giant cells | 7 (5.1%) | 68 (25%) | 0.000 | >0.05 |
| Remnant duct size at porta hepatis >150 μm <150 μm No ducts |
110 (79.7%) 19 (13.8%) 9 (6.5%) |
100 (36.8%) 89 (32.7%) 83 (30.5%) |
0.000 | >0.05 |
| Operative bleeding | 0 | 24 (8.8%) | 0.000 | >0.05 |
| Operative time(hours) (Mean ± SD) | 3.8 ± 1 | 4.4 ± 1.1 | 0.000 | 0.1 |
| Postoperative steroids | 94 (68.1%) | 22 (8.1%) | 0.000 | 0.000 |
| Early cholangitis | 10 (7.2%) | 98 (36%) | 0.000 | 0.001 |
| Early PHN | 1 (0.7%) | 53 (19.5) | 0.000 | >0.05 |
BA: Biliary atresia, BASM: Biliary atresia splenic malformation, TB: Total bilirubin, DB: Direct bilirubin, AST: Aspartate transaminase, Alb: Albumin, INR: International normalization ratio, PHN: Portal hypertension.