Fig. 2.

Recent strategies for regeneration of CNS (left) and PNS (right) by multifunctional bioscaffolds. CNS approach a) Scheme of cytokine-containing hydrogel embedded in a electrospun PCL scaffold composite b) Tissue bridging and neuronal axon regeneration observed by hematoxylin and eosin (H&E) staining and c) immunofluorescence staining of anti-microtubule-associated protein-2 (MAP2) neuron marker. PNS approach d,f) Scheme of fabrication of scaffolds composed of (−)-epigallocatechin gallate-loaded polycaprolactone using integrated molding and nerve conduit implantation in rat models e) anti‐oxidant marker NF-E2-related factor (Nrf2) immunofluorescent staining for RSCs on EGCG/PCL scaffolds. Reproduced with permission from Ref. [136]. Copyright © 2019 Cell Proliferation published by John Wiley & Sons Ltd. Reproduced with permission from Ref. [137]. Copyright 2020 RSC.