Table 4.
Treatment incidence per group (median, interquartile range, 2.5th percentile, 97.5th percentile) of antimicrobials for the intervention group and the control group.
| Treatment incidence 2017 | Treatment incidence 2018 | Treatment incidence 2019 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Median | IQR | 2.5th percentile | 97.5th percentile | Median | IQR | 2.5th percentile | 97.5th percentile | Median | IQR | 2.5th percentile | 97.5th percentile | ||
| IMMlact | IG | 6.35 | 10.24 | 0.00 | 39.34 | 4.21 | 9.95 | 0.00 | 30.65 | 7.37 | 10.36 | 0.00 | 40.35 |
| DDD per cow per 1,000 days | CG | 5.95 | 10.70 | 0.00 | 37.04 | 6.21 | 10.17 | 0.00 | 32.09 | ||||
| IMMlact HPCIA | IG | 0.00 | 0.65 | 0.00 | 10.00 | 0.00 | 0.00 | 0.00 | 5.88 | 0.00 | 0.57 | 0.00 | 7.22 |
| DDD per cow per 1,000 days | CG | 0.00 | 0.00 | 0.00 | 6.80 | 0.00 | 0.00 | 0.00 | 7.92 | ||||
| IMMdry | IG | 0.32 | 1.38 | 0.00 | 4.68 | 0.34 | 1.19 | 0.00 | 3.47 | 0.50 | 1.46 | 0.00 | 4.50 |
| DCD per cow per 1,000 days | CG | 0.33 | 1.36 | 0.00 | 5.07 | 0.45 | 1.57 | 0.00 | 4.64 | ||||
| SYSudd | IG | 0.48 | 1.88 | 0.00 | 9.24 | 0.55 | 1.97 | 0.00 | 9.26 | 0.85 | 1.92 | 0.00 | 6.47 |
| DDD per cow per 1,000 days | CG | 0.14 | 2.04 | 0.00 | 7.64 | 0.17 | 2.02 | 0.00 | 6.23 | ||||
| SYSudd HPCIA | IG | 0.00 | 0.04 | 0.00 | 3.07 | 0.00 | 0.00 | 0.00 | 3.40 | 0.00 | 0.06 | 0.00 | 2.21 |
| DDD per cow per 1,000 days | CG | 0.00 | 0.00 | 0.00 | 2.91 | 0.00 | 0.00 | 0.00 | 1.64 | ||||
| SYSute | IG | 0.00 | 0.47 | 0.00 | 1.51 | 0.00 | 0.47 | 0.00 | 2.84 | 0.00 | 0.24 | 0.00 | 3.03 |
| DDD per cow per 1,000 days | CG | 0.00 | 0.63 | 0.00 | 7.64 | 0.00 | 0.35 | 0.00 | 6.23 | ||||
| SYSute HPCIA | IG | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.59 | 0.00 | 0.00 | 0.00 | 0.00 |
| DDD per cow per 1,000 days | CG | 0.00 | 0.00 | 0.00 | 2.91 | 0.00 | 0.00 | 0.00 | 1.64 | ||||
| IUute | IG | 0.82 | 2.82 | 0.00 | 5.23 | 0.73 | 1.67 | 0.00 | 5.23 | 0.67 | 2.91 | 0.00 | 8.27 |
| DDD per cow per 1,000 days | CG | 0.58 | 2.75 | 0.00 | 7.54 | 0.51 | 2.14 | 0.00 | 8.89 | ||||
| CALFtot | IG | 5.25 | 18.32 | 0.00 | 73.23 | 1.76 | 14.1 | 0.00 | 112.03 | 0.74 | 7.09 | 0.00 | 64.47 |
| DDD per calf per 1,000 days | CG | 0.00 | 8.95 | 0.00 | 80.97 | 0.00 | 10.56 | 0.00 | 71.32 | ||||
| CALF tot HPCIA | IG | 0.00 | 1.58 | 0.00 | 21.97 | 0.00 | 0.00 | 0.00 | 38.75 | 0.00 | 0.00 | 0.00 | 8.24 |
| DDD per calf per 1,000 days | CG | 0.00 | 0.00 | 0.00 | 6.91 | 0.00 | 0.00 | 0.00 | 6.79 | ||||
| Other | IG | 2.18 | 5.35 | 0.00 | 26.12 | 2.46 | 4.70 | 0.00 | 22.55 | 2.03 | 5.21 | 0.00 | 25.00 |
| DDD per cow per 1,000 days | CG | 1.92 | 4.55 | 0.00 | 12.06 | 1.63 | 3.94 | 0.00 | 13.43 | ||||
| Other HPCIA | IG | 0.00 | 0.00 | 0.00 | 6.53 | 0.00 | 0.00 | 0.00 | 6.81 | 0.00 | 0.21 | 0.00 | 3.39 |
| DDD per cow per 1,000 days | CG | 0.00 | 0.00 | 0.00 | 4.34 | 0.00 | 0.00 | 0.00 | 1.81 | ||||
DDD, defined daily dose; DCD, defined course dose; IG, intervention group; CG, control group; IMMlact, intramammary use during lactation; IMMdry, Intramammary use for dry-off; SYSudd, Systemic use with indication udder health; SYSute, systemic use with indication uterine health; IUute, intrauterine application; CALFtot, use for calves; HPCIA, Highest priority critically important antimicrobials; IQR, interquartile range.