Illustration of FEM head model creation. A) Anatomical T1-weighted MR image. B) Manually generated lesion mask. C) Final segmentation masks including skin (orange), skull (yellow), CSF (blue), GM (dark green), and WM (light green). Masks were generated by using automated segmentation routines from SimNIBS, then combined with hand segmented lesion masks, and manually corrected. D) Final 3D FEM head model showing volume tetrahedra for the different tissue types (skin (orange), skull (yellow), CSF (blue), GM (gray), WM (white). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)