Table 4.

Estimated coefficients predicting depressive symptoms and phenotypes from IL-6, age, and their interaction.

	Depressed affect		Anhedonia		Somatic complaints		Interpersonal problems
R2	0.04***		0.03***		0.04***		0.036***
Predictor	b (SE)	p	b (SE)	p	b (SE)	p	b (SE)	p
Intercept	1.46 (0.12)	<0.001	3.46 (0.14)	<0.001	2.80 (0.13)	<0.001	0.39(0.04)	<0.001
IL-6	0.14 (0.09)	0.13	−0.28 (0.11)	0.01	0.32 (0.10)	0.0015	0.06 (0.03)	0.019
Age	−0.03 (0.01)	<0.001	0.005 (0.007)	0.50	−0.04 (0.01)	<0.001	−0.01 (0.002)	<0.001
IL-6 x age	−0.006 (0.006)	0.32	−0.005 (0.01)	0.48	0.01 (0.01)	0.10	−0.003 (0.002)	0.06
Covariates
Female	0.44 (0.12)	<0.001	−0.14 (0.14)	0.31	0.40 (0.13)	0.002	−0.03 (0.04)	0.37
Sub-study	0.05 (0.07)	0.46	0.24 (0.08)	0.002	0.07 (0.07)	0.34	0.01 (0.02)	0.47
BMI	0.03 (0.01)	0.01	−0.06 (0.01)	<0.001	0.04 (0.01)	<0.001	0.004 (0.003)	0.26

^***p < 0.001.