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. 2021 Jan 18;8:617758. doi: 10.3389/fcell.2020.617758

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Copyright © 2021 Liao, Wu, Wang, Wang, Wang, Gao, Zhong, Ma, Wu and Jiang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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OTUB1 promotes the proliferation and invasion of PCa cells. (A,B) Western blotting detecting the expression of OTUB1 in C4-2 and PC3 cells transfected with overexpression OTUB1, otub1 c91s, and OTUB1 siRNA. (C) Transwell assay in PC3 cell transfected with overexpression OTUB1 and otub1 c91s. (D) Transwell assay in PC3 cell transfected with OTUB1 siRNA. (E) Transwell assay in C4-2 cell transfected with OTUB1 overexpression and otub1 c91s. (F) Transwell assay in C4-2 cell transfected with OTUB1 siRNA. (G,H) Wound healing assay in PC3 and C4-2 cells transfected with OTUB1 overexpression, otub1 c91s, and OTUB1 siRNA. *P < 0.05; **P < 0.01; ****P < 0.001.