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. 2021 Jan 18;8:617758. doi: 10.3389/fcell.2020.617758

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Copyright © 2021 Liao, Wu, Wang, Wang, Wang, Gao, Zhong, Ma, Wu and Jiang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of increased OTUB1 expression on the cells cycle distribution of PC3 and C4-2 cells. (A,B) MTT assays in PC3 and C4-2 cells transfected with otub1 overexpression and otub1 c91s. (C,D) MTT assays in PC3 and C4-2 cells transfected with OTUB1 siRNA. (E,F) Colony formation assays in PC3 and C4-2 cells transfected with OTUB1 overexpression and otub1 c91s. (G,H) Colony formation assays in PC3 an C4-2 cells transfected with OTUB1 siRNA. (I,J) Effects of increased otub1 expression on the cell cycle distribution of PC3 (X² = 12.59; P = 0.0135) and C4-2 (X² = 15.17; P = 0.0044) cells. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.