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. 2021 Jan 18;8:619924. doi: 10.3389/fcell.2020.619924

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Copyright © 2021 Tang, Zhang, Lin, Xu, Chen, Wang, Zhang, Tang, Shi, Liu, Yang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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HIF-1α expression is concomitantly induced during the newly formation of corpus luteum. (A) Western analysis of HIF-1α and StAR expressions on Day 0 and 1 after pregnancy. (B) Summarized intensities of HIF-1α and StAR blotting normalized to the control (Day 0). (C) The expression changes of StAR in the presence or absence of echinomycin treatment on Day 1 after pregnancy. (D) Summarized intensities of StAR blotting normalized to the control (Day 0). (E) The expression changes of HIF-1α and StAR in luteinizing granulosa cells wtih hCG and CoCl2 treatment. (F) Summarized intensities of StAR blots normalized to the control (0 h). Each value represents the mean ± SE. One-way analysis of variance (ANOVA) was used to analyze the data, followed by a Tukey's multiple range test. n = 6. ^#P < 0.05, vs. the group in black; ^&P < 0.05, vs. the group in red.