TABLE 1.
Demographic and clinical data of the subjects.
| T2DM-MCI | T2DM-NC | HC | F-value (t/χ2) | P-values | |
| Numbers | 30 | 30 | 30 | – | – |
| Age (years) | 55.9 ± 6.54 | 54.97 ± 5.54 | 53.17 ± 6.57 | 1.491 | 0.231 |
| Sex (male/female) | 12/18 | 19/11 | 14/16 | 3.467 | 0.177a |
| Education (years) | 10.43 ± 2.94 | 11.90 ± 2.92 | 11.80 ± 2.99 | 2.316 | 0.105 |
| Diabetes duration (years) | 6.93 ± 5.46 | 7.93 ± 5.98 | – | 0.699 | 0.933 |
| BMI (kg/m2) | 25.59 ± 3.31 | 24.08 ± 3.02 | 23.45 ± 2.59 | 4.052 | 0.021* |
| Systolic blood pressure (mmHg) | 130.57 ± 18.25 | 131.37 ± 14.78 | 128.13 ± 18.10 | 0.194 | 0.749 |
| Diastolic blood pressure (mmHg) | 80.60 ± 10.33 | 82.90 ± 9.80 | 79.77 ± 9.17 | 0.895 | 0.441 |
| Fasting glucose (mmol/L) | 9.14 ± 3.05 | 8.56 ± 1.97 | 5.47 ± 0.63 | 25.769 | < 0.001*# |
| HbA1c (%) | 9.13 ± 2.07 | 8.84 ± 1.72 | 5.50 ± 0.36 | 49.505 | < 0.001*# |
| Total cholesterin (mmol/L) | 5.24 ± 1.45 | 4.96 ± 1.37 | 5.21 ± 0.96 | 0.432 | 0.651 |
| HDL cholesterin (mmol/L) | 1.16 ± 0.33 | 1.18 ± 0.30 | 1.40 ± 0.33 | 5.167 | 0.008*# |
| LDL cholesterin (mmol/L) | 3.36 ± 1.06 | 2.93 ± 0.78 | 3.10 ± 0.67 | 1.874 | 0.160 |
All subjects (T2DM-MCI, T2DM-NC, HC) were matched for age, sex, and education. Values are the mean ± standard deviation. aChi-square test for sex. The comparisons of demographic and clinical data among three groups were performed with ANOVA. The level of significance for intergroup differences was set at P < 0.05. * Denotes P < 0.017 (0.05/3) T2DM-MCI vs. HC with post hoc test, Bonferroni corrected. #Denotes P < 0.017 (0.05/3) T2DM-NC vs. HC with post hoc test, Bonferroni corrected. No significant difference was shown between T2DM-NC and T2DM-MCI with post hoc test, Bonferroni corrected. BMI, body mass index; HbA1c, glycosylated hemoglobin; HDL, high-density lipoprotein; LDL, low-density lipoprotein.