TABLE 3.

Differences in the white matter volume among T2DM-MCI, T2DM-NC, and HC groups.

Regions	White matter volume			F-values	ANOVA
	HC	T2DM-NC	T2DM-MCI		(P-values)
Left isthmus cingulate	3,931.40 ± 569.78	3,819.84 ± 570.83	3,470.82 ± 603.25	5.122	0.048
Left lateral orbitofrontal gyrus	6,700.99 ± 838.21	6,702.80 ± 570.27	6,267.02 ± 770.28	3.500	0.042
Left posterior cingulate	4,379.01 ± 610.81	4,652.48 ± 500.46	4,231.84 ± 441.51	5.010	0.027*
Left precuneus	9,442.53 ± 1,743.27	9,833.90 ± 1,242.31	8,847.39 ± 1,264.13	3.593	0.048*
Left insula	8,918.20 ± 946.21	9,140.63 ± 746.48	8,618.25 ± 695.40	3.194	0.046*
Right lateral orbitofrontal gyrus	6,569.96 ± 721.97	6,734.11 ± 641.00	6,196.94 ± 765.54	4.492	0.049*
Right pars orbitalis	1,134.16 ± 232.18	1,209.77 ± 168.79	1,063.01 ± 187.21	4.128	0.044*
Right rostral middle frontal gyrus	12,509.42 ± 2,160.15	12,959.35 ± 1,604.56	11,768.02 ± 1,791.73	3.116	0.049*
Right temporal pole	687.63 ± 128.12	745.50 ± 113.06	669.06 ± 119.51	3.290	0.049*

Values are the mean ± standard deviation. The comparisons of white matter volume of each region among three groups were performed with ANOVA. The level of significance for intergroup differences was set at P < 0.05, false discovery rate (FDR) corrected. * Denotes P < 0.017 (0.05/3) T2DM-MCI vs. T2DM-NC with post hoc test, Bonferroni corrected. No significant difference was shown between the T2DM-NC group and HC group with post hoc test, Bonferroni corrected.