Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 18;11:589304. doi: 10.3389/fimmu.2020.589304

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Schimunek, Lindberg, Cohen, Namas, Mi, Yin, Barclay, El-Dehaibi, Abboud, Zamora, Billiar and Vodovotz

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Principal component analysis of trauma patient sub-group data suggests a role for Type 3 immunity, in part regulated by Th17 cells, in the circulating inflammatory response to traumatic injury. Principal component analysis was carried out on the systemic inflammatory mediator data of Groups 1–3 as described in the Materials and Methods. (A) In Group 1, IL-22, IL-33, IL-23 IL-17E/IL-25, IL-13, and IL-10 were the principal characteristics. (B) In Group 2 patients, IL-1β, IL-22, IL-13, IL-4, IL-33, and IL-17A were the principal characteristics. (C) In Group 3, IL-10, IL-13, IL-22, IL-4, IL-33, and IL-1β were the principal characteristics.