TABLE 5.

Genes previously associated with breast cancer.

Genes	Reports	References
HCN4	HCN4 was highly correlated with lower survival rates of breast cancer.	Phan et al., 2017
RGPD3	30 most enriched new HOXB7 binding sites on breast cancer cell chromatin for which an annotated nearest gene exists: RGPD3, PIK3R1, etc.	Heinonen et al., 2015
EFCAB13	Variants that induce premature stop codons were identified in the DENND2D, EFCAB13, and TICRR genes.	Määttä et al., 2016
NFATC1	NFATC1 overexpression results in oncogenic BMI1transcriptional upregulation. Co-expression of FUNDC1 and BMI1 in BC patients predicted worse prognosis.	Wu et al., 2019
VAC14	VAC14 selectively prevents rapid degradation of Sac3.	Ikonomov et al., 2013
PRB2	A novel six-gene (TMEM252, PRB2, SMCO1, IVL, SMR3B, and COL9A3) signature was significantly associated with prognosis as an independent prognostic signature.	Lv et al., 2019
HIPK1	The deletion of the miR-200c/141 cluster resulted in increased tumor metastasis and inhibited tumor growth by directly upregulating the target gene HIPK1.	Liu et al., 2018
IRF2	Interferon regulatory factor 1 (IRF-1) and IRF-2 expression in breast cancer tissue microarrays.	Connett et al., 2005
HMGB2	Promotion of breast cancer progression by HMGB2.	Fu et al., 2018
FRMPD1	Rat Mcs5a is associated with breast cancer risk. Mcs5a1 is located within the ubiquitin ligase Fbxo10, whereas Mcs5a2 includes the 5′ portion of FRMPD1.	Samuelson et al., 2007
RPS27	The best ranked cancer immunotherapy proteins related to BC were RPS27, SUPT4H1, and CLPSL2.	López-Cortés et al., 2020
PTPRR	PTPRR and myocyte enhancer factor 2C (MEF2C) genes were upregulated in the classical MAPK and p38 MAPK pathways.	Motaghed et al., 2014