Table 5.
SNP crossover (XO) loci in the extended MHC class I OR gene region.
| Haplotype sequence alignment | OR GENE CLUSTER REGION/GABBR1/MOG | Total SNPs | XO point in haplotype sequence ID_HAP1 | Within or between (/) RE | XO between (/) genes | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| GPX5 to OR2H1 | MAS1L & LINC01015 | USB & OR2H2 | GABBR1 | MOG & ZFP57 | ||||||
| AA | A | B | C | D | A-D | |||||
| ID_HAP1 | ID-HAP2 | 960 kb | SNP/50 kb | SNP/50 kb | SNP/50 kb | SNP/60 kb | SNP/210 kb | |||
| 49_A*33-C*08:02 | 50_A*33-C*14:03 | SRR | 87 | 56 | 17 | 216 (XO) | 376 | 208524 A/G | ERV3-16A3 | F segment |
| 15_A*26-C*05 | 64_A*26-C*12:03 | SRR | 39 | 44 | 21 | 214 (XO) | 318 | 211345 A/G | ERV3-16A3 | F segment |
| 15_A*26-C*05 | 69_A*66-C*12:03 | SRR | 45 | 34 | 11 | 19 (XO) | 109 | 210115 G/A | LTR43/ERV3 | F segment |
| 2_A*01-C*06 | 11_A*01-C*07 | SRR | 105 | 68 | 26 | 2 (XO) 1 | 202 | 165747 T/C | Charlie4/L3b | ZFP57/HLA-F |
| 2_A*01-C*06 | 16_A*01-C*07 | SRR | 93 | 64 | 21 | 2 (XO) 1 | 181 | 165747 T/C | Charlie4/L3b | ZFP57/HLA-F |
| 4_A*03-C*07:02 | 7_A*03-C*06:02 | SRR | 97 | 43 | 4 (XO) | 3 | 147 | 121130 A/C | L3b/MER5 | GABBR1/MOG |
| 9_A*32-C*05 | 22_A*32-C*12:03 | SRR | 90 | 51 | 17(XO) 0 | 2 | 160 | 143183 T/C | AluY/L2 | GABBR1/MOG |
| 9_A*32-C*05 | 72_A*32-C*05 | SRR | 91 | 49 | 15 (XO) 0 | 2 | 157 | 143183 T/C | AluY/L2 | GABBR1/MOG |
| 10_A*02-C*12:03 | 17_A*02:17-C*03 | SRR | 93 | 30 (XO) 0 | 2 | 5 | 130 | 92214 G/A | AluY(Sc8) | OR2H2/GABBR1 |
| 10_A*02-C*12:03 | 92_A*02:12-C*01 | SRR | 91 | 30 (XO) 0 | 2 | 3 | 126 | 92214 G/A | AluY(Sc8) | OR2H2/GABBR1 |
| 5_A*02-C*05 | 10_A*02-C*12:03 | SRR | 77 | 32 (XO) 0 | 0 | 2 | 111 | 75758 T/C | MER21C | USB/OR2H2 |
| 10_A*02-C*12:03 | 5_A*02-C*05 | SRR | 77 | 32 (XO) 0 | 0 | 2 | 111 | 75792 C/T | MER21C | USB/OR2H2 |
| 34_A*24-C*03:04 | 68_A*24-C*04 | SRR | 97 | 15 (XO) 0 | 1 | 0 | 113 | 59547 C/T | LTR10A | USB/OR2H2 |
| 46_A*31-C*15:02 | 73_A*31-C*01:02 | SRR | 58 | 9 (XO) 2 | 2 | 6 | 75 | 59532 T/C | LTR10A | USB/OR2H2 |
| 15_A*26-C*05 | 84_A*26-C*07 | SRR | 37 | 20 (XO) 1 | 2 | 0 | 59 | 66738 A/T | Tigger2b-Pri | USB/OR2H2 |
| 22_A*32-C*12:03 | 72_A*32-C*05 | (XO) | 2 | 1 | 4 | 0 | 7 | 136748 T/C | L2/L1 | OR12D3/OR12D2 |
| 4_A*03-C*07:02 | 6_A*03-C*07:02 | 6_missing seq | 4 | 0 | 0 | 4 | Undetected | SPR from block AA to block D | ||
| 78_A*29-C*16 | 79_A*29-C*16 | 79_missing seq | 0 | 0 | 1 | 1 | Undetected | SPR from block AA to block D | ||
| 11_A*01-C*07 | 16_A*01-C*07 | 7 | 0 | 0 | 1 | 0 | 1 | Undetected | SPR from block AA to block D | |
| 4_A*03-C*07:02 | 51_A*03-C*07:02 | 8 | 0 | 0 | 0 | 1 | 1 | undetected | SPR from block AA to block D | |
| 34_A*24-C*03:04 | 94_A*24-C*03:04 | 0 | 0 | 0 | 2 | 1 | 3 | Undetected | SPR from block AA to block D | |
| 25_A*30-C*05 | 26_A*30-C*05 | 0 | 0 | 1 | 0 | 0 | 1 | Undetected | SPR from block AA to block D | |
| 46_A*31-C*15:02 | 82_A*31-C*03:04 | 0 | 0 | 2 | 1 | 4 | 7 | Undetected | SPR from block AA to block D | |
| 15_A*26-C*05 | 78_A*29-C*16 | SRR | 45 | 37 (XOa) 0 | 3 | 4 (XOb) | 89 | 91066 G/A | L2/MS | OR2H2/GABBR1 |
| 2_A*01-C*06 | 17_A*02:17-C*03 | SRR | 11 | 58 | 48 | 197 | 314 | |||
| 25_A*30-C*05 | 34_A*24-C*03:04 | SRR | 49 | 40 | 85 | 191 | 365 | |||
| 25_A*30-C*05 | 46_A*31-C*15:02 | SRR | 49 | 35 | 27 | 287 | 398 | |||
| 25_A*30-C*05 | 22_A*32-C*12:03 | SRR | 83 | 42 | 13 | 51 | 189 | |||
SRR is SNP-rich region, SPR is SNP-poor region, XO is crossing over, and numbers in the block columns AA to A–D are SNP counts per block.