Table 8.
SNP crossover (XO) loci within intergenic regions between HLA-B and MICA or MICB in alignments of different haplotype pairs.
| Alignments between paired haplotype sequences | XO distance from HLA-B | XO | XO within gene or within and between (/) repeat elements | |
|---|---|---|---|---|
| Lab ID numbers precede haplotypes | SNP | |||
| Haplotype 1 | Haplotype 2 | SPR/SRR | ||
| 65_B*14:01/MICA*019/MICB*502 | 49_B*14:02/MICA*011/MICB*502 | 8796 | T/C | L1 |
| 65_B*14:01/MICA*019/MICB*502 | 87_B*14:01/MICA*11/MICB*005:02 | 8822 | G/A | L1 |
| 72_B*44/MICA*008/MICB*005 | 83_B*44:03/MICA*004/MICB*005 | 14436 | A/G | L1M5/L1ME3 |
| 72_B*44/MICA*008/MICB*005 | 50_B*44:03/MICA*004/MICB*005 | 14436 | A/G | L1M5/L1ME3 |
| 25_B*18/MICA*001MICB*5002 | 30_B*18/MICA*018/MICB*201 | 16711 | G/T | L1 |
| 19_B*08/MICA*008/MICB*008 | 84_B*08/MICA*008/MICB*004 | 30243 | C/T | MLT2C1/Charlie9 |
| 94_B*51/MICA*006/MICB*005 | 92_B*51/MICA*010/MICB*005 | 44271 | A/G | LTR8A |
| 94_B*51/MICA*006/MICB*005 | 46_B*51/MICA*009/MICB*002 | 44618 | C/T | LTR8A/AluJb |
| 94_B*51/MICA*006/MICB*005 | 67_B*51/MICA*009/MICB*005 | 52042 | G/A | (CTC)n/L1M3 |
| 88_B*51/MICA*049/MICB*005 | 92_B*51/MICA*010/MICB*005 | 54075 | A/G | LTR8A |
| 54_B*35/MICA*002/MICB*005 | 68_B*35/MICA*016/MICB*002 | 66656/MICA | C/T | L1MB2/MIR in MICA |
| 46_B*51/MICA*009/MICB*002 | 67_B*51/MICA*009/MICB*005 | 95787 | C/T | L1PA3/Tigger3b |
| 86_B*40/MICA*008/MICB*002 | 82_B*40/MICA*008/MICB*004 | 96012 | C/T | L1PA3/Tigger3b |
| 88_B*51/MICA*049/MICB*005 | 94_B*51/MICA*006/MICB*005 | 100093 | G/A | THE1D/ L1M2 |
| 32_B*15/MICA*010/MICB*002 | 28_B*15/MICA*010/MICB*005 | 101267 | A/C | MER2 |
| 32_B*15/MICA*010/MICB*002 | 73_B*15/MICA*010/MICB*006 | 101267 | A/C | MER2 |
| 86_B*40/MICA*008/MICB*002 | 13_B*40/MICA*008/MICB*014 | 102370 | C/T | SVA-MIC indel |
| 21_B*35/MICA*002/MICB*005 | 1_B*35/MICA*002/MICB*002 | 105577 | G/C | MER21C/MER4 |
| 54_B*35/MICA*002/MICB*005 | 21_B*35/MICA*002/MICB*005 | 113437 | C/G | MER21C/MER4 |
| 68_B*35/MICA*016/MICB*002 | 23_B*35/MICA*16/MICB*005 | 116829 | G/A | 5′-ERV3-16A3_I (HCP5) |
| 54_B*35/MICA*002/MICB*005 | 1_B*35/MICA*002/MICB*002 | 119556 | A/G | 5′-ERV3-16A3_I |
| 88_B*51/MICA*049/MICB*005 | 46_B*51/MICA*009/MICB*002 | 123534 | G/C | 5′-ERV3-16A3_I |
| 88_B*51/MICA*049/MICB*005 | 67_B*51/MICA*009/MICB*005 | 123570 | C/T | 5′-ERV3-16A3_I |
| 38_B*40/MICA*027/MICB*005 | 71_B*40/MICA*027/MICB*013 | 124806 | A/G | THE1A/LTR33 |
| 28_B*15/MICA*010/MICB*005 | 73_B*15/MICA*010/MICB*006 | undetected | SPR | SPR HLA-B to MICB gene |
| 19_B*08/MICA*008/MICB*008 | 27_B*08/MICA*008/MICB*008 | no XO | SPR | SPR from HLA-B to MICB |
| 65_B*1401/MICA*019/MICB*502 | 49_B*1402/MICA*011/MICB*502 | SRR/112318/SPR | A/G | 5′-ERV3-16A3 (HCP5) |
| 65_B*1401/MICA*019/MICB*502 | 87_B*14:01/MICA*11/MICB*005:02 | SRR/146518/SPR | C/T | L1 |
| 38_B*40/MICA*027/MICB*005 | 86_B*40/MICA*008/MICB*002 | undetected | SRR | SRR from HLA-B to MICB |
| 38_B*40/MICA*027/MICB*005 | 82_B*40/MICA*008/MICB*004 | undetected | SRR | SRR from HLA-B to MICB |
| 54_B*35/MICA*002/MICB*005 | 35_B*35/MICA*017/MICB*003 | undetected | SRR | SRR from HLA-B to MICB |
SRR is SNP-rich region, SPR is SNP-poor region, and XO is crossover.