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. 2021 Jan 18;11:540591. doi: 10.3389/fphys.2020.540591

FIGURE 1.

FIGURE 1

Elevated mechanical stretch suppresses ACE2 and increases ACE expression in the aorta in vivo. (A) ACE2 and ACE mRNA expression in the aortas of the aortic constriction group and the sham group by RT-qPCR. (B,C) ACE2 and ACE protein levels in the aortas of the aortic constriction group and the sham group by Western blot. (D) Representative immunohistochemical staining of ACE2 and ACE in sections from the aortas of the aortic constriction group and the sham operation group. (E) Representative photomicrographs of immunohistochemical staining of ACE2 in the paracancerous tissues of patients with hypertension or without. Values are expressed as means ± SEM. *P < 0.05 vs. sham (n = 4).