FIGURE 5.
Effect of baicalin on macrophage infiltration and MCP-1 secretion. (A) Immunohistochemistry staining for F4/80 in different groups; the brown color shows positive cells (original magnification, × 400). (B) MCP-1 mRNA levels in the pancreas determined by RT-PCR. Values are shown as mean ± SD (n = 4). **p < 0.01 vs. control; ## p < 0.01 vs. CP group. (C) Immunohistochemistry staining for MCP-1 in different groups; the brown color shows positive cells (original magnification, ×400). (D) MCP-1 concentrations in the PSC culture supernatant were measured by ELISA, and values are shown as mean ± SD (n = 3). **p < 0.01 vs. control; ## p < 0.01 vs. TGF-β1 group. (E) Migration ability of macrophages in different groups was detected by the wound healing assay.