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. 2021 Jan 18;7:627774. doi: 10.3389/fmolb.2020.627774

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Copyright © 2021 Zhang, Chen, Zhu, Zhu, Liao, Wu, Cheng, Zhang, Mei and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Knockdown of GACAT3 decreased cell motility. After transfection of GACAT3 CRISPR-Cas13 or negative control CRISPR-Cas13, wound healing assay was used to detect cell motility changes in bladder cancer cells. (A) Representative images of wound healing assay in 5637 and T24 cells. (B) Decreased cell motility was observed in 5637 and T24 cells. Data are indicated as mean ± SD. Each experiment in both cell lines was performed in triplicate for three independent times.