Table 3.
Multiple linear regression analysis for duration of hospital stays in patients with COVID-19
| Variables | Duration of hospital stay | |||
|---|---|---|---|---|
| Univariate | Multivariate | |||
| Coefficients (95% CI) | P value | Coefficients (95% CI) | P value | |
| Sex (M/F) | 0.87 (− 1.26 to 3.01) | 0.42 | ||
| Age | 0.05 (− 0.03 to 0.14) | 0.20 | ||
| Comorbidities (yes/no) | 2.52 (0.40 to 4.64) | 0.02 | 2.267 (0.311 to 4.223) | 0.024 |
| Onset of symptom to hospital admission (days) | − 0.11 (− 0.24 to 0.02) | 0.10 | ||
| Lung region distribution (CT, bilateral/unilateral) | 0.47 (− 4.56 to 5.50) | 0.85 | ||
| Degree of lung involvement (CT, < 25%/25–50%/> 50%) | 1.40 (− 0.19 to 3.00) | 0.08 | ||
| Transverse distribution (CT, peripheral/diffuse) | 0.88 (− 1.27 to 3.02) | 0.42 | ||
| Oxygen supply | 1.82 (0.43 to 3.22) | 0.01 | ||
| Leukocyte count at admission (× 109/L) | 0.03 (− 0.39 to 0.46) | 0.87 | ||
| Delta leukocyte count (× 109/L)! | 0.60 (0.07 to 1.13) | 0.03 | ||
| Delta leukocyte count (× 109/L)!! | 0.43 (0.12 to 0.73) | 0.01 | ||
| ANC at admission (× 109/L) | 0.19 (− 0.33 to 0.71) | 0.47 | ||
| Delta ANC (× 109/L)! | 0.58 (− 0.001 to 1.163) | 0.05 | ||
| Delta ANC (× 109/L)!! | 0.41 (0.09 to 0.73) | 0.01 | ||
| ALC at presentation (× 109/L) | − 1.05 (− 2.74 to 0.64) | 0.22 | ||
| Delta ALC (× 109/L)! | 3.66 (1.10 to 6.21) | 0.005 | ||
| Delta ALC (× 109/L)!! | 3.49 (1.17 to 5.81) | 0.003 | ||
| AMC at presentation (× 109/L) | 1.22 (− 2.88 to 5.32) | 0.56 | ||
| Delta AMC (× 109/L)! | 8.49 (1.77 to 15.20) | 0.014 | ||
| Delta AMC (× 109/L)!! | 8.60 (4.01 to 13.19) | < 0.001 | ||
| AEC at presentation (× 109/L) | − 13.45 (− 25.78 to − 1.13) | 0.03 | ||
| Delta AEC (× 109/L)! | 14.27 (4.91 to 23.64) | 0.003 | 10.32 (1.03 to 19.60) | 0.030 |
| Delta AEC (× 109/L)!! | 12.27 (4.00 to 20.53) | 0.004 | ||
| ABC at presentation (× 109/L) | 3.31 (− 55.19 to 61.81) | 0.91 | ||
| Delta ABC (× 109/L)! | 71.35 (10.27 to 132.43) | 0.02 | ||
| Delta ABC (× 109/L)!! | 120.21 (57.74 to 182.68) | < 0.001 | 71.43 (8.55 to 134.31) | 0.026 |
| Platelet count at presentation (× 109/L) | − 0.0005 (− 0.01 to 0.010) | 0.92 | ||
| Delta PLT (× 109/L)! | 0.020 (0.003 to 0.036) | 0.019 | ||
| Delta PLT (× 109/L)!! | 0.027 (0.012 to 0.041) | 0.001 | ||
| HGB at presentation (g/L) | − 0.008 (− 0.067 to 0.051) | 0.79 | ||
| Delta HGB (g/L)! | 0.130 (0.024 to 0.236) | 0.016 | ||
| Delta HGB (g/L)!! | 0.144 (0.049 to 0.238) | 0.003 | ||
| MCV at presentation (fL) | − 0.10 (− 0.26 to 0.06) | 0.23 | ||
| Delta MCV (fL)! | 0.438 (− 0.048 to 0.924) | 0.077 | ||
| Delta MCV (fL)!! | 0.501 (0.093 to 0.909) | 0.016 | ||
| MCHC at presentation (g/L) | 0.02 (− 0.05 to 0.08) | 0.55 | ||
| Delta MCHC (g/L)! | 0.056 (− 0.019 to 0.132) | 0.144 | ||
| Delta MCHC (g/L)!! | 0.077 (0.011 to 0.143) | 0.023 | ||
M, male; F, female; ANC, absolute neutrophil count; ALC, absolute lymphocyte count; AMC, absolute monocyte count; AEC, absolute eosinophil count; ABC, absolute basophil count; PLT, platelet; HGB, hemoglobin; MCV, mean corpuscular volume; MCHC, mean cell hemoglobin concentration. Delta ! = end hospitalization − baseline; Delta ! ! = Max − Min