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. 2019 Jul 12;27(7):779–788. doi: 10.3727/096504018X15442985680348

Figure 1.

Figure 1

Elevated transforming growth factor-β (TGF-β) and protease-activated receptor 2 (PAR2) expression among colorectal cancer CRC patients after 5-fluorouracil (5-FU) therapy. (A) Analysis of TGF-β and PAR2 in RNA extracted from CRC tumor biopsies before chemotherapy (before) and after chemotherapy (after). (B) Comparison of differences in TGF-β and PAR2 expression between aggressive and nonaggressive tumor tissues. (C) Analysis of MMP2, MMP9, and PAI-1 in RNA extracted from CRC tumor biopsies before chemotherapy (before) and after chemotherapy (after). *p < 0.05, **p < 0.01, ***p < 0.001.