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PFN2 overexpression activated the PI3K/Akt/β-catenin signaling pathway. (A) Phosphorylation of Akt at Ser473 and Thr308, phosphorylation of GSK3β at Ser9, and the expression of β-catenin were significantly upregulated in OSC-19 cells with PFN2 overexpression. (B) Statistical analysis of each protein expression. Data were expressed as mean ± SEM from five independent experiments, n = 5. **p < 0.01.
