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. 2018 Dec 27;27(1):107–115. doi: 10.3727/096504018X15205622257163

Figure 5.

Figure 5

miR-200a affected the biological behaviors of GL15 cells via modulation of Rac1. (A) GL15 cells were transfected with miR-200a mimic, pEX-Rac1, or their corresponding negative controls (mimic NC and pEX). (B) Cell viability was detected by cell counting kit-8 (CCK-8) assay. (C) Cell migration and (D) cell invasion were detected by Transwell assay. (E) Apoptotic cell rate was detected by flow cytometry. (F) Protein level expression of apoptosis-associated protein was detected by Western blot analyses. Data were expressed as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001 (ANOVA).