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. 2019 Feb 21;27(3):317–323. doi: 10.3727/096504018X15228863026239

Figure 4.

Figure 4

MYB was overexpressed in melanoma. (A) Relative expression of MYB in melanoma cell lines. (B) qRT-PCR analysis for the expression of MYB in melanoma tissues and paired normal tissues. (C) Western blot was used to analyze the protein levels of MYB in pairs of melanoma tissues and normal tissues. (D) MYB expression was downregulated in A375 and WM35 cells transfected with siMYB. (E) CCK-8 assay was used to measure cell proliferation in A375 and WM35 cells transfected with siMYB or siNC. (F, G) Transwell assay was utilized to determine the migration and invasion in A375 and WM35 cells transfected with siMYB or siNC. *p < 0.05 and **p < 0.01.