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. 2018 Dec 27;27(1):99–106. doi: 10.3727/096504018X15195193936573

Figure 2.

Figure 2

lncRNA XIST promotes CRC cell migration and invasion possible via regulating epithelial–mesenchymal transition (EMT). HT29 cells were transfected with pc-XIST and blank control, while LoVo cells were transfected with si-XIST and si-control. (A) lncRNA XIST expression in the different transfected cells after 48 h of transfection. (B) MTT assay showed cell viability in the different transfected groups. Transwell assays showed (C) cell migration and (D) invasion in the different transfected groups, respectively. (E) The expression of EMT markers, including E-cadherin, N-cadherin, and vimentin, in the different transfected cells. Data were expressed as mean ± SD. *p < 0.05, **p < 0.01, and ***p < 0.001 compared to corresponding control.