Skip to main content
. 2019 Sep 23;27(9):1043–1050. doi: 10.3727/096504019X15560124931900

Figure 4.

Figure 4

Rac1 3′-UTRs are potential targets of miR-146a. (A) A luciferase reporter of Rac1 3′-UTR was constructed, which contained the binding sites of miR-146a, as predicted by bioinformatics analysis. A luciferase reporter of Rac1 3′-UTR containing mutated binding sites of miR-146a was also constructed. (B) miR-146a inhibited the luciferase activity of the reporter containing the Rac1 3′-UTR in MDA-MB-231 cells. However, miR-146a could not inhibit the luciferase activity of the reporter containing a mutated sequence of the Rac1 3′-UTR. **p < 0.01 versus control oligo group.