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. 2019 Feb 21;27(3):379–387. doi: 10.3727/096504018X15199531937158

Figure 1.

Figure 1

Cancer susceptibility candidate 2 (CASC2) was downexpressed in breast cancer (BC) tissues, metastasis tissues, and BC cell lines. (A) Downregulated CASC2 was defined in BC tissues and matched healthy tissues by real-time quantitative polymerase chain reaction (RT-qPCR). (B) RT-qPCR was used to determine the expression level of CASC2 in cancer tissues with or without metastasis. (C) The positive correlation between CASC2 expression and TNM stage was detected in BC. (D) The expression levels of CASC2 in three BC cell lines (LCC9, MDA-MB-231, and MCF-7) and a healthy breast cell line (HCC1937) were detected by RT-qPCR. Error bars represented the mean ± standard deviation (SD) of at least three independent experiments. **p < 0.01 versus control group.