Table 1.

Inclusion and exclusion criteria for the PREVAIL-P study.

Age/sex	Men and women 30–65 years of age, Postmenopausal females permitted
BMI/Physical activity	25–40 kg/m2 at enrollment, current sedentary status
Informed Consent	The capability and willingness to provide written informed consent
Exclusion Criteria
Significant CVD or disorders		Including, but not limited to, serious arrhythmias, cardiomyopathy, congestive heart failure, stroke or transient ischemic attacks, peripheral vascular disease, acute, chronic or recurrent thrombophlebitis or myocardial infarction/stroke, postmenopausal women
Diabetes		Previous diagnosis or taking medication for type 1 or 2 diabetes, fasting blood glucose ≥126 mg/dL
Blood pressure		Systolic blood pressure ≥160 mmHg or diastolic blood pressure ≥100 mmHg [44].
Other medical conditions		Including, but not limited to, chronic or recurrent respiratory, gastrointestinal, neuromuscular, neurological, HIV or psychiatric conditions. Hospitalization over the last 5 years or currently treatment for mental illness. Major joint issues or gait that would be contraindicated for exercise training. Conditions which are life-threatening or can be aggravated by exercise training
Other exclusions		Plans to be away from the Pitt County area more than 3 weeks in the next 3 months. Pregnant or plans to become pregnant. Currently engaging a diet or a weight loss program. Do not own smartphone for MyFitnessPal and Centrepoint Apps. Non-compliance during screening visits.