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. 2019 Feb 5;27(2):253–260. doi: 10.3727/096504018X15242763477504

Figure 2.

Figure 2

miR-1284 overexpression inhibited cell proliferation, migration, and invasion. (A) RT-qPCR was used to check the expression of miR-1284 in MDA-MB-231 and BT549 cells transduced with miR-1284 mimics or controls. (B) Cell counting kit-8 (CCK-8) assays for cellular proliferation analysis. (C) Colony formation assays indicated that overexpression of miR-1284 significantly inhibited the colony number. (D, E) Transwell assays were utilized to evaluate the migration and invasion of MDA-MB-231 and BT549 cells transfected with miR-1284 mimics or controls. (F) The effect of miR-1284 on MDA-MB-231 and BT549 cell apoptosis was determined by annexin V/PI staining. *p < 0.05.