Suppression of miR-381 reversed the effects of CAT104 knockdown on osteosarcoma cells. (A) Viability, (B) migration, (C) invasion, and (D) apoptosis of OS-732 cells after sh-CAT104 and/or miR-381 inhibitor transfection were detected using MTT assay, two-chamber migration (invasion) assay, and Guava Nexin assay, respectively. (E) Western blotting was performed to analyze the expressions of Bcl-2, Bax, caspase 3, and caspase 9 in OS-732 cells after sh-CAT104 and/or miR-381 inhibitor transfection. *p < 0.05, **p < 0.01, ***p < 0.001.