Figure 5.
Emodin suppressed EMT by regulating the Wnt/β-catenin signaling pathway. Cells in the control group were treated with vehicle. Cells in the experimental group were treated with 20 μmol/L emodin or with the combination of emodin (20 μmol/L) and LiCl (10 mmol/L) for 24 h. (A) The detection of E-cadherin and N-cadherin expression by Western blot. (B) Quantification of (A). (C) The detection of MMP-7 and VEGF expression by Western blot. (D) Quantification of (C). All the tests were repeated at least three times. GAPDH was used as an internal reference. **p < 0.01 versus the control group, #p < 0.05 versus the emodin 20 μmol/L group.