Figure 2.
Krüppel-like factor 5 (KLF5) was a direct target of miR-152 in CC. (A) The wild-type (WT) and mutant (Mut) miR-152 binding sequence in the 3′-UTR of KLF5. (B) Correlation between miR-152 and KLF5 expression in CC tissues. (C) Relative luciferase activity of HeLa and C33A cells cotransfected with miR-152 mimic or control and WT or Mut KLF5 3′-UTR. Relative KLF5 (D) mRNA and (E) protein expressions of KLF5 in HeLa and C33A cells transfected with miR-152 mimic and control. **p < 0.01.