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. 2019 Mar 29;27(4):423–429. doi: 10.3727/096504017X15030178624579

Figure 1.

Figure 1

Low lactamase β (LACTB) expression predicted a worse prognosis for patients with glioma. LACTB expression in glioma tissues and normal brain tissues from the Gene Expression Omnibus (GEO) (A) and The Cancer Genome Atlas (TCGA) (B) data sets. LACTB expression in 98 glioma tissues and 10 normal brain tissues was tested by immunohistochemistry (IHC; scale bars: 50 μm, 400×) (C) and statistical quantification of the mean optical density (D) in normal brain tissues and glioma tissues (*p < 0.001). Survival analysis of patients with glioma from the TCGA data sets (E) and our data (F). Real-time reverse transcription quantitative PCR (RT-qPCR) (G) and Western blot analysis (H, I) of LACTB in eight glioma tissues and paired adjacent nontumor tissues. ***p < 0.001. RT-qPCR (J) and Western blot analysis (K, L) of LACTB in four glioma cell lines.