Table 4.

Multiple regression analysis of clinical features associated with ABCB4 gene variations in patients with LPAC syndrome.

Clinical features	Estimate	SE	OR (95% CI)	p value
History of CBD lithiasis	0.57	0.17	3.1 (1.6–6.2)	<0.001
Chronic elevation of GGT	0.58	0.18	3.2 (1.6–6.6)	0.001
Personal/family history of hepato-biliary cancer	0.80	0.38	5.0 (1.2–25.5)	0.026

The p values for the likelihood ratio Chi-square test. ABCB4, ATP-binding cassette subfamily B member 4; CBD, common bile duct; GGT, gamma-glutamyltransferase; LPAC, low-phospholipid-associated cholelithiasis; OR, odds ratio.